Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella enterica serovar Typhimurium
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Salmonella Typhimurium is an important pathogen of human and animals. It shows a broad growth range and survives in harsh conditions. The aim of this study was to analyze transcriptional responses to a number of growth and stress conditions as well as the relationship of metabolic pathways and/or cell functions at the genome-scale-level by network analysis, and further to explore whether highly connected genes (hubs) in these networks were essential for growth, stress adaptation and virulence.
Originalsprog | Engelsk |
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Artikelnummer | 294 |
Tidsskrift | B M C Microbiology |
Vol/bind | 13 |
Antal sider | 16 |
ISSN | 1471-2180 |
DOI | |
Status | Udgivet - 2013 |
- Det Sundhedsvidenskabelige Fakultet - Salmonella, regulation, metabolism, genom scale network
Forskningsområder
ID: 92299428